Eva Kaufmann
Dr. Kaufmann鈥檚 research program explores the role of hematopoietic stem cells and trained immunity (鈥渋nnate immune memory鈥�) in allergic diseases. Her work focuses on respiratory allergies affecting both the upper and lower airways, including allergic rhinitis and asthma. By investigating the fundamental mechanisms of allergy development, her team aims to pave the way for new preventive and therapeutic strategies. The Kaufmann Lab integrates animal models with human samples, applying advanced flow cytometry, imaging, and single-cell sequencing, alongside functional in vitro and in vivo approaches, to connect basic discovery with translational impact.
Dr. Eva Kaufmann studied Veterinary Medicine in Germany, complemented by research fellowships in South Africa and the USA. She earned her PhD in Immunology at the German Federal Institute for Vaccines and Biomedicines, with a visiting scientist appointment at IPBS Toulouse, where she investigated lipopeptide-specific T cell responses in BCG vaccination. As a postdoctoral fellow at 蘑菇短视频, she advanced research on trained immunity and hematopoietic stem cell dynamics in tuberculosis, and later explored SARS-CoV-2 vaccination strategies. In 2022, Dr. Kaufmann joined Queen鈥檚 University as an Assistant Professor and Canada Research Chair in Immunology and Inflammation, establishing the Kaufmann Lab with its research focus on innate memory responses in allergic diseases. In 2025, Dr. Kaufmann was recruited back to 蘑菇短视频 as a tenure-track Assistant Professor in the Faculty of Dental Medicine and Oral Health Sciences, with her group based at the Meakins-Christie Laboratories of the RI-MUHC.
DVM, Justus Liebig University, Giessen, Germany
PhD, Paul-Ehrlich Institut Langen and JLU Giessen, Germany
- Trained immunity
- Hematopoietic stem cells
- Allergic diseases
- Respiratory diseases
- Canada Research Chair Tier 2 in Immunology and Inflammation (2023-2025, not transferable from Queen鈥檚 University to 蘑菇短视频)
- CIHR Peer Review Outstanding Contributions Recognition
- Keystone Symposia Future of Science Scholarship
- MGH Foundation Award
- Emil Skamene Prize
- German Society for Immunology Werner Mueller Award
- FRQS Rel猫ve Etoile Jacques Genest
- AAI Young Investigator Award
- CIHR Postdoctoral Fellowship
- FRQS Postdoctoral Fellowship
- German Research Foundation Postdoctoral Fellowship
- German National Academic Foundation PhD Scholarship
- German National Academic Foundation Undergraduate Scholarship
Kaufmann E*, Sanz J*, Dunn JL*, Khan N, Mendonca LE, Pacis A, Tzelepis F, Pernet E, Dumaine A, Grenier JC, Mailhot-L茅onard F, Ahmed E, Belle J, Besla R, Mazer B, King IL, Nijnik A, Robbins CS, Barreiro LB, Divangahi M. (2018) BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell 172:176鈥�190
Kaufmann E, Landekic M, Downey J, Chronopoulos J, Teimouri Neyhad S, Tran K, Vinh DC, Barreiro LB, Divangahi M. (2022) Lack of evidence for intergenerational inheritance of immune resistance to infections. Nat Immunol. 23:203-207
Kaufmann E*, Khan N*, Tran KA, Ulndreaj A, Pernet E, Fontes G, Lupien A, Desmeules P, McIntosh F, Abow A, Moorlag SJCFM, Debisarun P, Mossman K, Banerjee A, Karo-Atar D, Sadeghi M, Mubareka S, Vinh DC, King IL, Robbins CS, Behr MA, Netea MG, Joubert P, Divangahi M. (2022) BCG vaccination provides protection against IAV but not SARS-CoV-2. Cell Rep. 38:110502
Li Q, Liang F, Bhattarai S, Divangahi M, Kaufmann E, Petrof BJ. (2024) Dynamic equilibrium of skeletal muscle macrophage ontogeny in the diaphragm during homeostasis, injury, and recovery. Scientific Rep. 14:9132
Sheedy FJ and Kaufmann E.鈥� (2024) Breaking the Cycle 鈥� TCA-metabolism drives DNA methylation changes in immune tolerance. Proc Natl Acad Sci USA. 121:e2419751121
Bhattarai S*, Kaufmann E*, Liang F, Zheng Y, Gusev E, Hamid Q, Ding J, Divangahi M, Petrof B. (2025) Characterization of viral entry genes and impact of SARS-CoV-2 infection in the diaphragm and other skeletal muscles. Journal of Cachexia, Sarcopenia and Muscle 16:e13705
Tran BT*, Jeyanathan V*,#, Cao R*, Kaufmann E鈥�, King KY鈥�. (2025). Hematopoietic Stem and Progenitor Cells as Reservoir for Trained Immunity. eLife. 14: e106610.
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