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UID:20250806T050135EDT-4103hDeFic@132.216.98.100
DTSTAMP:20250806T090135Z
DESCRIPTION:The Centre of Excellence in Epilepsy at The Neuro (Montreal Neu
 rological Institute-Hospital) is proud to announce the new Epilepsy Lectur
 e Series. The series will include eight lectures per year covering hot top
 ics in basic and clinical epilepsy research. Topics will be presented by d
 istinguished leaders and rising stars in the field\, with the goal of brid
 ging basic and clinical perspectives. \n\nTo register: eventbrite\n\nLink 
 to livestreaming here (Q&A function is not accessible)\n\nSpeaker: Dr. Car
 rie McDonald\n	Professor of Radiation Oncology and Psychiatry\n\nNeuropsych
 ologist at the University of California\, San Diego\n\nTalk Abstract - Ove
 r the past decade\, the conceptualization of epilepsy as a network disorde
 r has revolutionized our approach to the study of seizures\, as well as ps
 ychiatric and cognitive co-morbidities in epilepsy. Brain imaging has been
  at the forefront of this movement\, shifting the focus from one of identi
 fying epileptic lesions to one defining epileptogenic networks. In paralle
 l\, the study of cognitive impairments in epilepsy has shifted from the st
 udy of isolated cognitive impairments within epilepsy syndromes (e.g.\, me
 mory impairments in temporal lobe epilepsy\; TLE) to one that emphasizes c
 ognitive and psychiatric profiles within and across epilepsy syndromes—or 
 cognitive phenotyping. In this talk\, Dr. McDonald will describe a 15- yea
 r NIH-funded program of research using advanced\, quantitative structural\
 , functional\, and diffusion imaging to characterize the neural substrates
  underlying cognitive co-morbidities in patients with epilepsy. Her talk w
 ill highlight network abnormalities associated with cognitive phenotypes i
 n TLE and describe how these patterns may be useful for identifying patien
 ts at risk for progressive cognitive decline. She will also describe netwo
 rk features that predict individualized risk for cognitive decline followi
 ng epilepsy surgery\, as well as possible mechanisms of cognitive reserve.
  Finally\, Dr. McDonald will review the need to consider how patient-speci
 fic risk and resilience factors\, including bilingualism\, can influence b
 rain and neuropsychological profiles and could modify risk for post-operat
 ive cognitive decline. Future efforts discussed will include the need to h
 armonize neuropsychological approaches to cognitive phenotyping for deploy
 ment in large-scale\, international studies. Such global efforts are essen
 tial to determine the reproducibility and generalizability of the current 
 findings\, accelerate scientific discoveries\, and advance personalized me
 dicine in epilepsy.\n
DTSTART:20220421T200000Z
DTEND:20220421T210000Z
SUMMARY:NEURO Epilepsy Lecture Series: Imaging Brain Networks in Epilepsy: 
 Determining the Neural Basis of Cognitive and Clinical Co-Morbidities (vir
 tual event)
URL:/neuro/channels/event/neuro-epilepsy-lecture-serie
 s-imaging-brain-networks-epilepsy-determining-neural-basis-cognitive-and-3
 38054
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