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Dr. Simon Thebault is a neurologist specializing in multiple sclerosis (MS) and neuroimmunology. His research focuses on developing and translating actionable soluble and immune cell biomarkers to improve patient outcomes. Bridging the gap between laboratory innovation and clinical care, his lab employs advanced detection technologies and multiomic approaches to analyze biospecimens from well-characterized clinical cohorts.

Key research areas include validating the clinical utility of emerging serum biomarkers such as neurofilament light chain and glial fibrillary acidic protein, characterizing cerebrospinal fluid protein and immune cell profiles as indicators of CNS-compartmentalized inflammation, and investigating the role of Epstein-Barr virus in priming disease activity in MS, both as a potential biomarker and a therapeutic target.

"MS is a condition that affects people in their prime and over the last couple of decades we've developed treatments that can really radically alter the trajectory of disease. It's a very hopeful disease to treat on the clinical side, but similarly, on the research side, I still think there's a lot of work to be done. By developing these biomarkers, perhaps we can bring much more precision to the treatment of patients with MS." - Dr. Thebault

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